This scientific paper reviews the current state of research on the Thwaites Glacier in West Antarctica, and outlines key research objectives for the next decade. The paper focuses on understanding the drivers, boundary conditions, and processes involved in the potential collapse of the Thwaites Glacier, which could significantly contribute to global sea-level rise. The authors emphasize the importance of a comprehensive, international research effort to study the complex interaction of the atmosphere, ocean, and ice sheet in this region, including a detailed mapping of the glacier’s bed and internal structure, as well as continuous monitoring of surface elevation, ice flow speed, and ocean conditions. By addressing these research objectives, scientists hope to improve our understanding of how quickly the Thwaites Glacier might collapse and the resulting impact on sea levels around the world.